Tottenham Hotspur will be without the services of Steven Bergwijn, Ryan Sessegnon and Cristian Romero for Saturday's Premier League clash with Watford.
The London club did not suffer any fresh issues against Southampton on Tuesday, though, with the decision to substitute Sergio Reguilon at the interval purely tactical.
Reguilon is expected to keep his spot in the starting XI for this match, while the back three are also unlikely to be disturbed, with Davinson Sanchez playing alongside Eric Dier and Ben Davies.
Head coach Antonio Conte has full of praise for Harry Winks during Thursday's pre-match press conference, and the Englishman is expected to retain his spot in the middle of the park.
Dele Alli started against the Saints before being replaced by Lucas Moura just past the hour, and the latter is now likely to come into the starting side alongside Harry Kane and Son Heung-min.
Conte will again send his side out in a 3-4-3 formation, with Emerson Royal featuring as the right-sided wing-back, while Pierre-Emile Hojbjerg will start in central midfield.
Tanguy Ndombele and Bryan Gil are also options to feature in an attacking area, but both players are expected to start on the bench for the London club, while fit-again Giovani Lo Celso could return to the squad.
Tottenham Hotspur possible starting lineup: Lloris; Sanchez, Dier, Davies; Emerson, Winks, Hojbjerg, Reguilon; Son, Kane, Lucas
