Barcelona are reportedly working to offload Gerard Pique, Jordi Alba, Sergi Roberto and Sergio Busquets at the end of the 2022-23 campaign.
Busquets's current deal is due to expire next summer, and the experienced midfielder is widely expected to depart on a free transfer, with a number of MLS clubs said to be in the hunt for his signature.
Pique and Alba have both lost their starting roles this term, meanwhile, and there has been a host of speculation surrounding their futures at Camp Nou.
Roberto signed a new deal with Barcelona last June, but the contract will only run until next summer, and according to ESPN, Xavi's side are working to offload all four players.
The report claims that Barcelona value Roberto's ability to play in a number of positions, but the club are planning to add a new right-back next summer and also want to boost their midfield, which would push the Spaniard down the pecking order.
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Busquets and Roberto could ultimately leave on free transfers at the end of the season, but Pique has a deal at Camp Nou until June 2024, with the 35-year-old signing an extension in October 2020.
The centre-back has made seven appearances at club level this term, but his recent involvement has largely been due to injuries in the middle of the defence.
Pique was booed by a section of Barcelona fans during Thursday's 3-0 win over Villarreal, with the defender appearing for the final 12 months of the contest.
During his pre-match press conference, the club's head coach Xavi branded the former Spain international "a great captain" and called for "unity" at Camp Nou.
"At the Gamper I called for unity. It's time to be together. All I can say is that in the dressing room he is an example. And he's a great captain. People need to know that," said the manager.
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"I don't know why they whistle and I don't care either. What matters to me is that Pique is with us in the dressing room and he always does the best for the group. Today the reaction was required and the team reacted wonderfully. I'm happy to be Pique's coach."
Alba, meanwhile, also has another 18 months left to run on his contract at Barcelona, but the 33-year-old will allegedly be surplus to requirements next year.
The Spaniard has made eight appearances at club level this term, but he faces competition from Marcos Alonso and Alejandro Balde for the starting role at left-back.
Barcelona are believed to have attempted to offload the defender to Inter Milan in the latter stages of the summer transfer window.
Both Alba and Pique are said to be owed large sums by the Catalan outfit in deferred wages due to the financial problems that were worsened by the coronavirus outbreak.
