The clubs meet having both risen near to the top of the Serie A form table, with Verona just a point behind their hosts, who sit seventh after a tumultuous opening ten games.
Chief architects of Lazio's recent success, Sergej Milinkovic-Savic and Ciro Immobile both starred against Club Brugge in midweek, as the club qualified for the last-16 of the Champions League for the first time in 20 years with a 2-2 draw at the Olimpico.
Last season's capocannoniere Immobile won and converted a penalty in the first half, while Luis Alberto - another key man who has been absent due to COVID-19 infection earlier this season - ran the game from midfield.
It was surely a deserved qualification, as the Aquile went unbeaten throughout a hard-fought Group F campaign disrupted by both illness and injury. In the aftermath, coach Simone Inzaghi claimed such progress was "like a trophy" for his experienced outfit, which had previously underwhelmed when on continental duty.
That cherished achievement followed a lacklustre and rather fortunate win over Spezia last weekend, when the Aquile prevailed despite being clearly outplayed by the promoted Ligurian outfit.
Milinkovic-Savic and Immobile - now with 11 goals in 12 appearances in all competitions - were the goalscorers then too, and their return to form and fitness suggests brighter times ahead for Inzaghi's side.
If precedent is anything to go by, the afterglow can linger on for Lazio this week, as the Biancocelesti have won six of their last seven league games against Saturday's opponents Verona.
Lazio have in fact won 23 points out of 27 at home against the Gialloblu in the three-points-per-win era, having scored 30 goals against them in the process. That represents their best goals-per-game average (of 3.3) against any top-flight club.
However, the Aquile have conceded 17 goals after the first 10 games this season, their worst tally at this stage since 1992-93 and have won only one of their five home games in Serie A this term. Both of those statistics must markedly improve if they are to mount any kind of Scudetto challenge in the spring.
After a recent upturn in results - though they were knocked out of the Coppa Italia last month - Verona are currently eighth after 10 games, with a healthy return of 16 points.
Ivan Juric's well-drilled side drew 1-1 with mid-table counterparts Cagliari last week and have generally provided a positive output, even after losing some of their better players in the summer.
Their Croat coach is often cited as a major factor in the club's ascendancy, leading the team to successive seasons of fighting things out in the top half despite a relatively modest squad.
Verona midfielder Mattia Zaccagni, in particular, has attracted the attention of several top teams in Italy - including Saturday's opponents Lazio - due to his consistently impressive performances this term.
With two goals and four assists so far, Zaccagni was called up to Roberto Mancini's Azzurri squad for the first time in November and may even prove an outside contender for a place in Italy's selection at next summer's Euros.
Playing in behind lone striker Samuel Di Carmine, the Cesena-born player helped Verona to win their last away fixture against Atalanta, after a long streak of nine draws and five defeats on the road.
The Gialloblu last won consecutive away top-flight games in 2014 however, so victory in Rome may prove a bridge too far for Zaccagni and company.
Lazio Serie A form: WWDWLW
Lazio form (all competitions): WWLDWD
Hellas Verona Serie A form: DWDLWD
Hellas Verona form (all competitions): WDLLWD
Defender Matteo Lovato is expected to replace the suspended Federico Ceccherini in the Gialloblu's usual 3-4-2-1 setup, with livewires Antonin Barak and Mattia Zaccagni playing in support of lone striker Samuel Di Carmine.
Hosts Lazio have a handful of players missing for what could prove to be a stern challenge of their credentials, with influential midfielder Luis Alberto, centre-backs Patric and Luiz Felipe, striker Vedat Muriqi and captain Senad Lulic all out injured.
Lazio possible starting lineup:
Strakosha; Hoedt, Acerbi, Radu; Lazzari, Milinkovic-Savic, Leiva, Akpa Akpro, Fares; Correa, Immobile
Hellas Verona possible starting lineup:
Silvestri; Magnani, Dawidowicz, Lovato; Faraoni, Tameze, Veloso, Lazovic; Zaccagni, Barak; Di Carmine
We say: Lazio 2-2 Hellas Verona
Lazio striker Ciro Immobile has scored a goal in each of his last five league games and - ominously for Saturday's opponents - registered his last Serie A hat-trick against Verona in July.
But while the Azzurri star can expect to continue his hot streak at home, adventurous Verona are more than capable of prising open a patched-up Lazio defence more than once at Stadio Olimpico.