The R's have not won since the first game of the season and are starting to show signs of missing key players who have either been sold, or are absent through injury.
QPR currently sit 16th in the table and will be concerned by the lack of creative spark in the final third, something they will be desperate to rectify as soon as possible.
They will take heart however from the fact that they have only lost once in the last five games against the Blues; a 4-3 loss at home.
Like QPR, City are also in search of their first win since the opening day of the season and have lost their last two 1-0.
After producing a relatively solid start to the season, Aitor Karanka's men have slipped to just six points from six games and will feel they need to use the busy upcoming schedule to get back to winning ways.
The Blues have shored up their defence, having conceded only four times in their first six matches – compared to 12 from their final half-dozen fixtures last season
Improved defensive displays have come hand-in-hand with something of a goal drought though, with Birmingham having only scored three in the first six games – two from corners and one from the penalty spot.
Queens Park Rangers Championship form: WLDDD
Queens Park Rangers form (all competitions): LWLDDD
Birmingham City Championship form: WDDDLL
Birmingham City form (all competitions): WDDDLL
Mark Warburton will hope to welcome back Lyndon Dykes, but may be forced to wait given the severity of his thigh injury.
Warburton also mentioned in post-match interviews that he felt his team lacked quality all over the pitch, and therefore could look to reshuffle his pack ahead of this match.
City will be without the suspended Adam Clayton and Karanka may look to use this setback as an opportunity to make an attacking adjustment to his starting lineup.
If not, Karanka will likely replace Clayton with recent signing Mikel San Jose
Queens Park Rangers possible starting lineup:
Dieng; Kakay, Dickie, Barbet, Wallace; Amos, Cameron; Osayi-Samuel, Chair, Willock, Bonne
Birmingham City possible starting lineup:
Etheridge; Colin, Dean, Friend, Pedersen; Gardner, San Jose; Leko, McGree, Bela; Hogan
We say: Queens Park Rangers 0-0 Birmingham City
Both sides have not been at their best of late, and we are anticipating a scrappy affair as these two battle it out for the points. As such, it may be that neither manages to break the deadlock, resulting in a 0-0 draw.