Leeds have a six-point lead over third-placed Brentford before the Bees take on Preston North End on Wednesday, while Barnsley are three points adrift of safety at this very late stage.
There have been some inevitable blips along the way, but Leeds' Premier League dream is set to come to fruition as they boast a two-point lead atop the Championship rankings with three games remaining.
West Bromwich Albion missed the chance to temporarily overtake Leeds as the Baggies were held to a goalless draw by fellow promotion hopefuls Fulham on Tuesday, and Leeds have a brilliant chance to move even further clear in the race for automatic promotion with a win on Thursday.
Marcelo Bielsa's side were forced to do it the hard way against Swansea City on Sunday, however, with Pablo Hernandez netting an 89th-minute winner off the bench to extend the Whites' winning run in the second tier to three games.
The 2-0 defeat to Cardiff City following the return of the Championship was simply a minor setback on Leeds' journey back to the big time, and if Brentford fail to take all three points against Preston, Bielsa's side can confirm their promotion to the Premier League with victory over Barnsley.
The Whites have tasted success in five out of their last six matches on home soil and have only conceded one goal in that time, although Bielsa will have to make do without Kalvin Phillips for the remainder of the campaign after the midfielder picked up a knee injury.
In contrast, Barnsley's survival hopes are looking all the more slim despite managing to hold an in-form Wigan Athletic side to a goalless stalemate last time out.
One defeat from six games since the second tier returned is not bad reading whatsoever, but the Championship's basement team are now three points adrift of Charlton Athletic with three games of the season remaining.
Gerhard Struber's men enjoyed victories over Queens Park Rangers and Blackburn Rovers in the month of June, leading to optimism that Barnsley could yet produce a great escape and rise above the dotted line in the latter stages of the campaign.
However, should the Tykes fail to win against Leeds and Charlton triumph over Birmingham City the day before, Struber's side may as well start packing their bags and begin preparations for an immediate return to League One - especially with their final two fixtures coming against promotion-chasing sides in Nottingham Forest and Brentford.
Leeds United Championship form: LWDWWW
Barnsley Championship form: WDWLDD
With Phillips set to miss out Leeds' remaining three games, Bielsa has confirmed that Ben White is set to deputise in midfield for the title hopefuls.
Following his late winner in the dying embers of the game against Swansea, Hernandez is likely to start in the middle of the park.
As for Barnsley, Romal Palmer will miss the rest of the season with a knee injury, but Struber otherwise has a clean bill of health as the Tykes look to keep their faint hopes of survival alive.
Leeds United possible starting lineup:
Meslier; Ayling, Cooper, Berardi, Dallas; White; Costa, Klich, Hernandez, Harrison; Bamford
Barnsley possible starting lineup:
Sahin-Radlinger; Sollbauer, Andersen, Halme; Ludewig, Mowatt, Styles, Ritzmaier; Woodrow; Brown, Chaplin
We say: Leeds United 3-0 Barnsley
The confidence of Bielsa's men will be through the roof at the moment, and Leeds have turned Elland Road into a fortress over the past few weeks. Barnsley are certainly trying to put up a fight as they attempt to pull off a miraculous escape from the relegation zone, but Leeds are the clear favourites for this one and their Premier League status could be confirmed by the close of play on Thursday.