Cardiff have released Sol Bamba, Joe Bennett, Junior Hoilett and Euro 2020-bound Wales midfielder Jonny Williams at the end of their contracts.
Bamba, Bennett and Hoilett joined the Bluebirds in 2016 and made a combined total of 478 appearances.
Defender Sol Bamba last month announced that he is cancer free following his battle with Non-Hodgkin lymphoma.
Williams, who signed from Charlton in February, and goalkeeper Joe Day are also leaving the club at the end of June.
A statement on Cardiff's website read: "Our departing Bluebirds will always be welcome here at Cardiff City Stadium and we wish them all the very best for the future."
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