Midfielder Wilshere has not featured all season because of a broken leg, while Rosicky has been limited to just one appearance because of a variety of complaints.
However, Wenger has revealed that the duo are now "progressing well".
"Wilshere and Rosicky are back in full training. Basically they are all progressing well," he told the club's official website.
Meanwhile, goalkeeper Cech has been sidelined since March 2 with a hamstring injury.
The weekend's home encounter against Watford may come too soon for the 33-year-old, but Wenger added that he is not far away from returning to action.
"Cech is going back to normal training. It's too early to say if he will be available for the weekend. He might be a bit short to be competitive," said the French boss.
The Gunners go into the clash against Watford in third place, 11 points behind leaders Leicester City.