Each player has endured an inconsistent domestic campaign with Chelsea missing out on the Champions League, and it has resulted in their omission from Julen Lopetegui's plans for the tournament in Russia.
Spain face games against Portugal, Iran and Morocco in the group stages.
Goalkeepers: David de Gea, Pepe Reina, Kepa Arrizabalaga
Defenders: Jordi Alba, Cesar Azpilicueta, Dani Carvajal, Nacho, Nacho Monreal, Alvaro Odriozola, Gerard Pique, Sergio Ramos
Midfielders: Isco, Thiago Alcantara, Sergio Busquets, David Silva, Andres Iniesta, Saul Niguez, Koke, Marco Asensio
Forwards: Iago Aspas, Diego Costa, Rodrigo, Lucas Vazquez