Thomas Partey has been passed fit to start for Arsenal against Everton, as Jorginho makes the bench at Goodison Park.
Partey emerged as a doubt for the contest after coming off with a rib injury at half time in last week's 1-0 FA Cup fourth-round defeat to Manchester City.
However, the Ghana midfielder did not sustain any serious damage and has been given the green light to line up in a full-strength Arsenal XI on Merseyside.
As a result, new signing Jorginho is among the substitutes ahead of a potential debut off the bench, while Leandro Trossard and Jakub Kiwior join the Italian in the dugout.
Fresh from signing a new long-term contract until 2027, Gabriel Martinelli joins Martin Odegaard, Bukayo Saka and Eddie Nketiah in the Gunners attack.
Granit Xhaka and Partey will man the midfield, as Ben White, Gabriel Magalhaes, William Saliba, Oleksandr Zinchenko and Aaron Ramsdale form a first-choice backline.
As for Everton, Sean Dyche has seemingly gone for a 4-3-3 formation in his first game in charge of the Toffees, as ex-Arsenal man Alex Iwobi starts against his former club.
Dwight McNeil - who starred under Dyche for Burnley - has also earned a recall to the first XI alongside Abdoulaye Doucoure, who joins Amadou Onana and Idrissa Gueye in the middle.
Arsenal starting lineup: Ramsdale; White, Saliba, Gabriel, Zinchenko; Xhaka, Partey; Saka, Odegaard, Martinelli; Nketiah
Subs: Turner, Tomiyasu, Holding, Kiwior, Tierney, Jorginho, Vieira, Trossard, Cozier-Duberry
Everton starting lineup: Pickford; Coleman, Coady, Tarkowski, Mykolenko; Onana, Gueye, Doucoure; Iwobi, Calvert-Lewin, McNeil
Subs: Begovic, Holgate, Mina, Godfrey, Vinagre, Davies, Gray, Maupay, Simms
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