Here, the PA news agency looks at of his some of his most significant goals.
May 1997 v Wimbledon
Owen scored on his senior Liverpool debut after coming on as a substitute to become, at the time, the Premier League's youngest goalscorer aged 17 years and 143 days.
June 1998 v Argentina
Arguably Owen's most famous strike. With England drawing 1-1 with Argentina in their World Cup last-16 clash, the striker raced on to David Beckham's pass to out-pace Jose Chamot, drift past Roberto Ayala and clip a shot across goalkeeper Carlos Roa.
May 2001 v Arsenal
Another typical Owen strike, this one to win the FA Cup. Having already produced a late equaliser in the final at the Millennium Stadium, he charged onto Patrik Berger's through-ball to beat Lee Dixon and covering centre-back Tony Adams to fire a narrow-angle left-footed shot just inside the far post.
September 2001 v Germany
Not dissimilar to his goal against Argentina, Owen this time received a pass from Steven Gerrard and advanced into the area to fire high past Oliver Kahn, completing his hat-trick in England's 5-1 World Cup qualifying win in Munich.
April 2005 v Barcelona
Not one of his most important goals but to score in a Clasico for Real
Madrid is a high point for any player. It helped secure a 4-2 win but could not prevent Barcelona ultimately winning La Liga by four points.
September 2009 v Man City
Injuries may have restricted Owen's starting opportunities at United but he still earned his place in club folklore with a dramatic injury-time derby winner against Manchester City at Old Trafford. Ryan Giggs threaded a pass into the area and Owen pounced from six yards to secure a 4-3 win.