Nuno arrived at Molineux last summer and after guiding Wolves to promotion to the Premier League, the Portuguese has been rewarded with a new three-year contract.
Bonatini has seen his previous loan spell turned into a permanent transfer and the new signing has said that the show of faith in his ability by Nuno is reciprocated.
The 24-year-old told the Express & Star: "Nuno knows exactly what to do, he's prepared everything and knows exactly how the other teams will play It's easy for us to go on the pitch and do our job.
"I have total faith in Nuno. Last season he showed to everyone that he deserves to be here, he knows what to do.
"We have 100% confidence in him. He knows every player, how everyone will play, you have to have faith in him and in each other as well. We have a very good team, good players to help us during the season so we are happy and we're preparing."
Bonatini contributed 12 goals and five assists in 43 Championship outings last season.