The Eagles beat Lens 2-1 in their opening fixture and are positioned third in the early standings, while Strasbourg went down 3-1 to Lorient in their first game back.
After finishing fifth in last season's revised Ligue 1 table, Nice have plenty to look forward to in 2020-21 as they are assured of a place in the Europa League group stage.
That European campaign is a long way off starting yet, though, so all focus will be on maintaining their early league momentum in order to improve on last term's finish.
Patrick Vieira's men were one of just four teams to collect maximum points on matchday one, along with Nimes, Lorient and Angers.
That victory only maintained the feel-good vibe at the club, having now lost just one of their last 13 Ligue 1 matches, with that loss coming against Nimes in January.
That includes a run of five away games without defeat, although that record could come under threat on Saturday as Strasbourg have won seven of their last 10 home Ligue 1 games.
Les Coureurs fell to defeat in their opening game of 2020-21, though, despite Mehdi Chahiri giving his side an early lead away at Lorient.
Going back into last season, Strasbourg have now conceded three goals or more in their last two Ligue 1 games - not since August 2017 have they registered a longer-such run.
The good news for Thierry Laurey's side ahead of this weekend is that they have lost just one of their last 15 home league meetings with Nice, winning eight of those.
Nice were unable to beat Strasbourg home and away last season, meanwhile, so this could prove to be a tricky assignment for Vieira's charges.
Strasbourg Ligue 1 form: L
Nice Ligue 1 form: W
Dimitri Lienard missed the Lorient defeat and remains doubtful for this match, meaning that Chahiri should retain his place in central midfield for Strasbourg.
Ludovic Ajorque's place in the side may also be in doubt, however, having failed to score in his last seven Ligue 1 games - his worst drought in the top flight.
As for Nice, they have a number of injury absentees, with Robson Bambu the latest to join the list of crocked players after limping off against Lens.
Strasbourg possible starting lineup:
Kawashima; Lala, Simakan, Dijku, Caci; Bellegarde, Sissoko, Chahiri; Thomasson; Waris, Ajorque
Nice possible starting lineup:
Benitez; Burner, Pelmard, Dante, Kamara; Lees-Melou, Schneiderlin, Thuram; Maurice, Dolberg, Gouiri
We say: Strasbourg 0-2 Nice
Nice kicked off their Ligue 1 campaign in a winning way and will be out to make it six points from six on Saturday. The visitors have scored in each of their last 11 league outings, and we expect that run to continue here in a fairly routine win.