Harry Kane broke Alan Shearer's 22-year record for Premier League goals scored in a calendar year as the forward netted a hat-trick, while Dele Alli and Son Heung-min also added goals during the second half.
Find out how all of the action unfolded in North London courtesy of Sports Mole's minute-by-minute updates below.
TOTTENHAM HOTSPUR SUBSTITUTES: Vorm, Trippier, Davies, Winks, Sissoko, Lamela, Llorente
SOUTHAMPTON SUBSTITUTES: McCarthy, McQueen, Pied, Ward-Prowse, Davis, Tadic, Gabbiadini
If Kane can still improve, that only spells trouble for defences all over Europe...
TOTTENHAM HOTSPUR XI: Lloris; Aurier, Sanchez, Vertonghen, Rose; Dier, Dembele; Eriksen, Dele, Son; Kane
SOUTHAMPTON XI: Forster; Stephens, Yoshida, Hoedt, Targett; Romeu, Lemina, Hojbjerg; Boufal, Redmond, Long
If you would like to read our match report from today's game, you can do so by clicking here. Goodbye for now.