Meanwhile, Nacional welcome the frontrunners to the Madeira Stadium sitting in ninth position after their recent win over Tondela.
When playing host to Braga at the weekend, Sporting were at risk of seeing their lead reduced at the top of the table and fourth-placed Braga moving to within two points.
While Porto and Benfica have the quality to close down the current pacesetters, seeing Sporting extend their unbeaten start to 12 matches has kept the pressure on the nation's most high-profile clubs.
Ruben Amorim will refuse to get carried away by his side's ruthless streak in the top flight, but every win going forward will leave their nearest rivals unable to slip up in their own fixtures.
Amorin would have been relieved to see Goncalves end his two-match goalless run against Braga, taking his tally to 11 strikes in as many appearances.
Like the visitors, Nacional head into this contest on a high after registering an important 2-0 triumph over Tondela for just their third win in 11 games.
Luis Freire's side were helped by their opponents having two players sent off, although victory was far from routine for a club who had lost their previous three contests.
Although just three points separate Nacional and the relegation zone, Freire and his squad can at least go into this contest with little to lose against the in-form side in the country.
The Alvinegros have collected nine of their 13 points for the season at home, suffering just one defeat at the hands of Santa Clara.
Nacional Primeira Liga form: DWLLLW
Nacional form (all competitions): WLLLWW
Sporting Lisbon Primeira Liga form: WWDWWW
Sporting Lisbon form (all competitions): DWWWWW
Nunes will hope for a recall to the Sporting side after scoring as a substitute against Braga.
Having not played since December 27, Freire could opt against making any changes to his Nacional XI.
Abdullahi Ibrahim Alhassan is an alternative to Nuno Borges in the centre of midfield.
Nacional possible starting lineup:
Guimaraes; Freitas, Cesar, Kal, Vigario; Micael, Borges, Azouni; Riascos, Rochez, Camacho
Sporting Lisbon possible starting lineup:
Adan; Neto, Coates, Feddal; Porro, Palhinha, Mario, Mendes; Goncalves, Nunes; Tomas
We say: Nacional 0-2 Sporting Lisbon
On a high after their important success against Tondela, we expect a strong performance from Nacional on home territory. However, few teams are capable of stopping this Sporting team right now, and the visitors should outclass their hosts in the final third.