Paris Saint-Germain have made six changes to the team that defeated Shakhtar Donetsk in the Champions League on Tuesday.
Thiago Silva, Serge Aurier and Maxwell come into the defence, with Thiago Motta returning to the starting lineup in midfield.
Angel di Maria and Edinson Cavani replace Ezequiel Lavezzi and Lucas Moura with Ibrahimovic continuing up front.
Maxwel Cornet continues on the wing for Lyon after scoring in midweek but Alexandre Lacazette misses out in favour of Claudio Beauvue.
Paris Saint-Germain: Trapp; Aurier, Silva, Luiz, Maxwell; Rabiot, Motta, Matuidi; Di Maria, Cavani, Ibrahimovic
Subs: Sirigu, Marquinhos, Kurzawa, Lavezzi, Rodrigues, Stambouli, Verratti
Lyon: Lopes; Rafael, Mapou, Morel, Bedimo; Gonalons, Ferri, Tolisso; Cornet, Grenier, Beauvue
Subs: Gorgelin, Darder, Del Castillo, Ghezzal, Kone, Malbranque, Mvuemba
