Pep Guardiola's side have won just two of their last seven Premier League games, including a 2-0 defeat at Tottenham Hotspur last time out, to leave them 13th in the table with almost a quarter of the season gone.
However, they did seal their place in the Champions League last 16 with two games to spare in midweek and Guardiola will be looking to take that European form into domestic duties now.
Here, Sports Mole rounds up all of Man City's latest injury and suspension news ahead of the contest.
Status: Major doubt
Type of injury: Hamstring
Possible return date: November 28 (vs. Burnley)
Nathan Ake picked up a hamstring injury while on international duty with Netherlands and, while he has now returned to training, Guardiola may consider Saturday's game to come too soon for the centre-back.
MANCHESTER CITY'S SUSPENSION LIST
Man City have no players suspended for this match.
Watch the Sports Mole Football Shorts prediction for this game below: