Juventus vs. Torino (Saturday, 4.15pm)
We say: Juventus 2-0 Torino
Torino are certainly capable of making it a difficult afternoon for the champions, but it is tough to back against Juve due to their excellent form. We fancy a relatively routine home victory, which would move Sarri's side seven points clear at the summit before second-placed Lazio take on Milan.
Sassuolo vs. Lecce (Saturday, 6.30pm)
The visitors are currently 18th in the table, one point behind 17th-placed Genoa, while Sassuolo occupy 12th position and recorded an impressive 3-1 win at Fiorentina on Wednesday night.
We say: Sassuolo 2-0 Lecce
Lecce's recent form is extremely poor, but Sassuolo will enter the match off the back of a fine result. The home side have a lot of talent in the final third of the field, and we fancy them to pick up all three points here.
Lazio vs. AC Milan (Saturday, 8.45pm)
Lazio's pursuit of Serie A leaders Juventus will continue on Saturday night when they welcome top-six hopefuls AC Milan to the Stadio Olimpico for what should be an enthralling clash.
The home side are currently second in the table, four points behind leaders Juventus, while Milan sit seventh, two points behind sixth-placed Napoli, who have a game in hand.
We say: Lazio 2-1 AC Milan
The fact that Lazio are missing their leading scorer is a huge boost for Milan, who will be determined to record their 13th league victory of the season. It would not be a surprise to see the two sides share the points, but we just fancy Lazio to sneak a victory despite their absentees.