Cottagers head coach Slavisa Jokanovic has been frustrated in the transfer market this summer at the same time as a number of players have left the club, but he has finally been able to push through a major addition.
The West Londoners have paid an undisclosed fee for Cisse, who has penned a three-year deal after agreeing to make the move to England.
The 23-year-old told the club's official website: "I am very happy to be here. It is a great opportunity at Fulham and I am looking forward to showing my qualities and what I can do."
The former Belgium Under-21 player made 27 appearances in all competitions last season, which included three outings in the Europa League.