League leaders Leyton Orient were thrashed 4-0 by Exeter City at St. James Park, as Tom Nichols scored twice from the penalty spot, with Alex Nicholls and David Wheeler rounding off the scoring.
Carlisle United came out on top in their five-goal thriller against Barnet, as Derek Asamoah netted a brace to give the home side all three points.
York City condemned Newport County to their fifth defeat of the season, leaving them bottom of League Two after goals from James Berrett, Reece Thompson and Vadaine Oliver won it comfortably for the away side.
Morecambe came back from two goals down to snatch all three points against 10-man Yeovil Town, after Shaun Jeffers saw a first-half red card in their 4-2 loss.
Wycombe Wanderers have moved up to second in the table, after they beat Hartlepool United 2-1, with the result being Pools's third defeat on the bounce.
Matt McClure bagged a first-half brace for Dagenham & Redbridge in their 2-1 away win at Northampton Town.
Luton Town comfortably overcame 10-man Cambridge United, as Luke Guttridge, Luke Wilkinson and Danny Green scored the goals for the away side.
Teddy Sheringham picked up another victory as Stevenage manager as his side beat high-flying Plymouth Argyle, with first-half goals from Connor Ogilvie and Chris Whelpdale gave the former England striker the victory.
Mansfield Town and AFC Wimbledon shared the spoils in their match, as Chris Clements cancelled out Tom Elliott's opener.
Portsmouth and Accrington Stanley played out the only goalless game in today's host of fixtures.
Results in full (half-time scores in brackets): Cambridge United 1-3 Luton Town (1-1), Carlisle United 3-2 Barnet (2-2), Exeter City 4-0 Leyton Orient (2-0), Mansfield Town 1-1 AFC Wimbledon (1-1), Newport County 0-3 York City (0-1), Northampton Town 1-2 Dagenham & Redbridge (1-2), Portsmouth 0-0 Accrington Stanley (0-0), Stevenage 2-1 Plymouth Argyle (2-0), Wycombe Wanderers 2-1 Hartlepool United (1-1), Yeovil Town 2-4 Morecambe (2-0).
