Arsenal boss Arsene Wenger has left striker Eddie Nketiah on the bench for the Europa League clash with Red Star Belgrade.
Nketiah had been in contention to start at the Emirates Stadium after his two-goal showing against Norwich City last week, but the youngster has to make do with a place among the replacements.
As expected, Wenger has made mass changes to his starting lineup, with Jack Wilshere, Theo Walcott and Olivier Giroud again being used in a cup tie.
Mathieu Debuchy features at the back after being reintegrated into the first-team setup, while Matt Macey deputises for the injured David Ospina.
Reiss Nelson and Ainsley Maitland-Niles have also been given more first-team experience as the Gunners look for the win which will guarantee their place in the last 32.
Red Star have made just the one change, with Marko Gobeljic replacing the suspended Milan Rodic.
Arsenal: Macey; Debuchy, Elneny, Holding; Nelson, Coquelin, Willock, Maitland-Miles; Wilshere, Walcott; Giroud
Subs: Cech, Osei-Tutu, Sheaf, Dasilva, McGuane, Akpom, Nketiah
Red Star Belgrade: Borjan; Stojkovic, Savic, Le Tallec, Gobeljic; Donald, Krsticic, Srnic, Kanga, Radonjic; Boakye
Subs: Frimpong, Radic, Adzic, Babic, Milic, Supic, Pesic
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