In contrast, the hosts go into the game following a 2-2 draw with West Ham United in which Brighton were pegged back by the capital outfit twice on Sunday.
Brighton & Hove Albion travelled to a high-flying West Ham United side hoping to end a five-game winless run in the top flight, with the Seagulls' position becoming more precarious by the week.
Graham Potter's men were unable to claim a much-needed victory as they played out a 2-2 draw with the Hammers on Sunday, with Neal Maupay and Lewis Dunk seeing goals cancelled out by Ben Johnson and Tomas Soucek respectively.
That point in the capital means that Brighton are still hovering just above the dotted line, but the Seagulls did manage to climb above Burnley into 16th after Sean Dyche's men fell short at Leeds United.
However, Burnley do have a game in hand over their fellow strugglers, with Brighton now playing out three consecutive draws following stalemates with relegation candidates Fulham and Sheffield United.
Brighton's underwhelming results this season have not been a true reflection of their performances, but after being pegged back twice against West Ham at the weekend, Potter's men cannot afford to feel sorry for themselves before welcoming Arsenal to the South Coast.
Mikel Arteta's Arsenal had not won in seven Premier League matches before welcoming Chelsea to the Emirates on Boxing Day, and most fans expected that to become eight against a title-chasing Blues side.
However, Arsenal produced arguably their best performance of the season to run out 3-1 winners in that London derby, with Alexandre Lacazette, Granit Xhaka and Bukayo Saka all finding the back of the net while Tammy Abraham pulled one back for Chelsea.
The Blues were nowhere near their best, but Arsenal's young crop played Frank Lampard's men off the park in North London and claimed a vital three points to distance themselves from the danger zone, with the Gunners now six clear of the bottom three as they aim to mount a charge for the top half.
Having finally managed to turn their fortunes around at home, the Gunners will now be aiming to win their first away match in the Premier League since a 1-0 win over Manchester United on November 1, with Arteta's side losing their last two top-flight matches on the road to Tottenham Hotspur and Everton respectively.
However, Arsenal are yet to win a Premier League game at the Amex Stadium and suffered back-to-back 2-1 defeats to Brighton last season, with Maupay set to renew hostilities with the Gunners after his last-minute winner and fracas with Arteta's squad in June.
Brighton & Hove Albion Premier League form: DLLDDD
Arsenal Premier League form: LLLDLW
Arsenal form (all competitions): WLDLLW
Brighton right-back Tariq Lamptey missed out the draw with the Hammers due to a hamstring issue, but Potter has reassured supporters that the highly-rated youngster's injury is not serious and he should be back soon.
Meanwhile, Arsenal centre-back Gabriel Magalhaes will miss this game and the Gunners' trip to West Bromwich Albion after coming into close contact with someone who tested positive for coronavirus.
Brighton & Hove Albion possible starting lineup:
Sanchez; Webster, Dunk, Burn; Veltman, Bissouma, Propper, March; Maupay, Trossard; Welbeck
Arsenal possible starting lineup:
Leno; Bellerin, Holding, Mari, Tierney; Xhaka, Ceballos; Pepe, Smith Rowe, Aubameyang; Lacazette
We say: Brighton & Hove Albion 1-2 Arsenal
Brighton have become somewhat of a bogey team for Arsenal since the Seagulls earned promotion to the big time, but the Gunners ought to be full of confidence after a dominant win over Chelsea. In contrast, Brighton would have been frustrated to only take one point home from their showdown with West Ham, and with Arsenal having had an extra day off to recover, we can see Arteta's men ending their Amex hoodoo with a narrow win.
Top betting tip
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