Seventeen days on from their rousing 4-2 victory over Tottenham Hotspur in the Premier League, Arsenal will look to do it all over again at the Emirates Stadium when they welcome their North London rivals in the EFL Cup.
The Gunners came roaring back to beat their neighbours in thrilling fashion on that occasion and a repeat on Wednesday will see them through to the semi-finals of the competition.
However, they are coming into the match off the back of a shock 3-2 defeat at Southampton at the weekend - a result which ended their 22-game unbeaten streak across all competitions.
Here, Sports Mole looks at how Unai Emery could set his side up for the derby.
Out: Konstantinos Mavropanos (groin), Rob Holding (knee), Emile Smith Rowe (hip), Hector bellerin (calf), Danny Welbeck (ankle)
Doubtful: Shkodran Mustafi (hamstring), Sead Kolasinac (quadriceps)
Emery must strike the balance between the usual rotation policy for this competition and the fact that this is both a quarter-final and a North London derby, all while competing against a growing injury list.
A makeshift three-man defence including Granit Xhaka and Stephan Lichtsteiner at centre-back did not work against Southampton, but Arsenal are boosted by the return of Sokratis Papastathopoulos from suspension for this one.
A lack of other options may mean that Laurent Koscielny is forced to start a second match in the space of just four days despite only recently returning from an injury lay-off, although Nacho Monreal is an option in the middle should Ainsley Maitland-Niles start on the left.
Emery does have more luxuries further up the field, where players with the quality of Mesut Ozil, Alexandre Lacazette and Aaron Ramsey can come into the team having not started at the weekend.
Henrikh Mkhitaryan scored twice at St Mary's and will hope that is enough to retain his place in the team, although Eddie Nketiah provides another option should Emery go for youth.
> Click here to see how Tottenham could line up for this fixture
