Already holding a six-point advantage over Rapid Vienna and Molde, the English and Norwegian sides are aware that they will move to the brink of the knockout stages with victory at the Emirates Stadium.
Most Arsenal supporters will agree that they have not enjoyed the fastest start to the season, already losing out to Liverpool, Manchester City and Leicester City in the Premier League.
However, despite suffering defeat to three of their rivals, the Gunners only remain four points adrift of first place courtesy of a deserved 1-0 triumph away at Manchester United on Sunday.
Nevertheless, the level of their overall performance would have impressed the Spaniard and the club's fans ahead of back-to-back home fixtures with Molde and Aston Villa.
Should Arsenal prevail in each contest, Arteta will be satisfied with the club's progress heading into the November international break, a feeling which he would not have expected when succumbing to Leicester on October 25.
Like their hosts, Molde would have had few complaints when learning the draw for the group stages, aware that it provided them with a realistic chance of reaching the last 32 of this competition for just the second time in their history.
As it stands, Erling Moe's side are taking full advantage of being presented with a favourable group, something which was welcomed after they missed out on Champions League football to Ferencvaros on away goals.
Molde initially required time to shake off conceding three times at home, but they have recently recorded six successive wins in all competitions.
Ohi Omoijuanfo has been the star of the show in recent weeks, scoring the decisive goals in the narrow successes over Dundalk and Rapid Vienna.
Arsenal Europa League form: WW
Arsenal form (all competitions): WLWLWW
Molde Europa League form: WW
Molde form (all competitions): WWWWWW
Arteta is expected to name a much stronger lineup to the side which started last week's fixture against Dundalk.
While David Luiz is back in contention after a thigh injury, the Brazilian may not be risked from the start.
Moe is expected to make a couple of changes to the team which faced Mjondalen at the weekend.
Martin Ellingsten will almost certainly be restored to the first XI after coming off the substitutes' bench to net a double in the 3-1 win.
Arsenal possible starting lineup:
Leno; Mustafi, Gabriel, Kolasinac; Soares, Xhaka, Ceballos, Maitland-Niles; Pepe, Nketiah, Nelson
Molde possible starting lineup:
Linde; Wingo, Bjornbak, Gregersen, Haugen; Aursnes, Eikrem, Ellingsen; Hestad, Omoijuanfo, Brynhildsen
We say: Arsenal 3-1 Molde
Having shown that they are capable of delivering strong second-half performances, Molde will fancy their chances of gaining a result against opposition who will likely include a number of fringe players. However, we cannot back against a Gunners squad who will want to take their chance to impress Arteta.