The fourth-place Whites marked their return to action following a two-month hiatus with a late draw against Randers, while Odense are down in ninth ahead of their first game back.
Aarhus needed a last-gasp goal from Patrick Mortensen to rescue their 1-1 draw on Thursday in a match that made headlines across the world.
In the absence of any spectators owing to the coronavirus pandemic, the club constructed a giant electronic wall around the pitch which contained the faces of thousands of fans.
Supporters watched on as Mortensen struck in added time to edge their side a step closer to a top-six finish, with a draw on Monday enough to achieve their aim.
With league leaders Midtjylland 21 points better off, though, the best David Nielsen's side can hope for in the championship round is finishing third to secure a Europa League playoff spot.
Odense also have plenty still to play for as the regular season enters its final two matches. They are seven points adrift of the top six, however, and will therefore be part of the relegation round.
The Striped will still have a chance to qualify for the Europa League should they finish best of the rest in the bottom half, so Jakob Michelsen will be desperate to get some points on the board on Monday.
Whereas Aarhus have already got one 90-minute runout under their belt, Odense have not been in action since a 1-1 draw with SonderjyskE on March 8.
That was their third league draw in a row in a nine-match winless run that stretches back to early November.
From being as high as fourth after the 16th round of fixtures, Odense have slipped all the way down to ninth and desperately need to stop the rot.
Achieving that on Monday will be a big ask, however, as Aarhus are unbeaten in five at home - taking nine points from 15 - while Odense have not won any of their last six on their travels.
Aarhus' Superliga form: DWWDLD
Odense's Superliga form: DLLDDD
Head To Head
Aarhus have lost only one of the last eight meetings between the sides, winning both of the last two.
The Whites were 1-0 winners when the sides last faced off, courtesy of a late Jakob Ankersen goal in their Danish Cup round-of-16 tie seven months ago.
We say: Aarhus 2-0 Odense
Odense are at a disadvantage as this is their first game back following a near three-month break. Aarhus were fortunate to avoid defeat last time out, but they are unbeaten in five at home and are the clear favourites here.